产品货号：
Z26579
中文名称：
SLC12A3抗体
英文名称：
Anti-SLC12A3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SLC12A3 Antibody |
| 指标别名 | solute carrier family 12 member 3;NCC;NCCT;TSC;SLC12A3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rabbit,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SLC12A3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human SLC12A3(310-328aa EDKASKGFFSYRADIFVQN),different from the related mouse sequence by three amino acids,and from the related rat sequence by four amino acids. |
| 实际分子量 | 131KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Solute carrier family 12(sodium/chloride transporters),member 3,also called NCCT or TSC,encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis.This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule.By fluorescence in situ hybridization,this gene is mapped to 16q13.Mutations in this gene cause Gitelman syndrome,a disease similar to Bartter's syndrome,that is characterized by hypokalemic alkalosis combined with hypomagnesemia,low urinary calcium,and increased renin activity associated with normal blood pressure.This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. |
| Uniprot ID | P55017 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | solute carrier family 12(sodium/chloride transporters),member 3 |
| 蛋白名全称 | Solute carrier family 12 member 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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